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Alejandro Bravo-Cuellar Selected Research

Pentoxifylline (Trental)

3/2021Sensitizing the cytotoxic action of Docetaxel induced by Pentoxifylline in a PC3 prostate cancer cell line.
1/2020Pentoxifylline Sensitizes Cisplatin-Resistant Human Cervical Cancer Cells to Cisplatin Treatment: Involvement of Mitochondrial and NF-Kappa B Pathways.
3/2019Pentoxifylline Enhances the Apoptotic Effect of Carboplatin in Y79 Retinoblastoma Cells.
10/2018Treatment of hepatocarcinoma with celecoxib and pentoxifylline: a case report
1/2018Pentoxifylline Added to Steroid Window Treatment Phase Modified Apoptotic Gene Expression in Pediatric Patients With Acute Lymphoblastic Leukemia.
3/2013Addition of pentoxifylline to pegylated interferon-alpha-2a and ribavirin improves sustained virological response to chronic hepatitis C virus: a randomized clinical trial.
2/2013Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65.
11/2011Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
12/2010[In vitro induction of apoptosis in acute myelogenous and lymphoblastic leukemia cells by adriamycine is increased by pentoxifylline].
5/2010Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence.
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Alejandro Bravo-Cuellar Research Topics

Disease

17Neoplasms (Cancer)
08/2022 - 03/2006
8Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2020 - 01/2008
4Leukemia
02/2014 - 12/2011
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2018 - 12/2010
2Prostatic Neoplasms (Prostate Cancer)
08/2022 - 03/2021
2Breast Neoplasms (Breast Cancer)
12/2020 - 05/2015
2Retinoblastoma (Glioblastoma, Retinal)
03/2019 - 05/2003
1Triple Negative Breast Neoplasms
12/2020
1Urinary Tract Infections (Urinary Tract Infection)
01/2019
1Carcinoma (Carcinomatosis)
01/2019
1Hematologic Neoplasms (Hematological Malignancy)
11/2013
1Infections
03/2013
1Chronic Hepatitis C
03/2013
1Diabetic Foot
03/2012
1Wounds and Injuries (Trauma)
03/2012
1Carcinogenesis
02/2012
1Seizures (Absence Seizure)
09/2011
1Necrosis
08/2008
1Lymphoma (Lymphomas)
03/2006

Drug/Important Bio-Agent (IBA)

11Pentoxifylline (Trental)FDA LinkGeneric
03/2021 - 03/2006
5NF-kappa B (NF-kB)IBA
01/2020 - 11/2011
5Doxorubicin (Adriamycin)FDA LinkGeneric
01/2020 - 03/2006
5Proteins (Proteins, Gene)FDA Link
02/2013 - 05/2003
4CaspasesIBA
12/2020 - 03/2006
4Transcription Factors (Transcription Factor)IBA
03/2019 - 02/2013
4LigandsIBA
11/2013 - 06/2011
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2022 - 01/2019
3CytokinesIBA
08/2022 - 08/2008
3Pharmaceutical PreparationsIBA
01/2020 - 05/2010
2Carboplatin (JM8)FDA LinkGeneric
01/2020 - 03/2019
2Antineoplastic Agents (Antineoplastics)IBA
01/2020 - 02/2014
2Cisplatin (Platino)FDA LinkGeneric
01/2020 - 11/2011
2XanthineIBA
01/2020 - 01/2018
2Anti-Bacterial Agents (Antibiotics)IBA
01/2019 - 03/2012
2Interleukin-6 (Interleukin 6)IBA
12/2016 - 08/2008
2Proteasome InhibitorsIBA
02/2014 - 02/2013
2benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
02/2014 - 02/2013
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2014 - 08/2008
2micaIBA
06/2011 - 01/2008
2DNA (Deoxyribonucleic Acid)IBA
03/2006 - 05/2003
1statticIBA
08/2022
1Cadherins (E-Cadherin)IBA
08/2022
1VimentinIBA
08/2022
1Cytokine Receptors (Cytokine Receptor)IBA
08/2022
1ChemokinesIBA
08/2022
1Phosphotransferases (Kinase)IBA
08/2022
1tocilizumab (atlizumab)FDA Link
08/2022
1Hormones (Hormone)IBA
03/2021
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
03/2021
1Docetaxel (Taxotere)FDA Link
03/2021
1alliin (PCSO)IBA
12/2020
1Phenobarbital (Luminal)FDA Link
12/2020
1allicinIBA
12/2020
1InterleukinsIBA
01/2020
1I-kappa B Proteins (I kappa B)IBA
03/2019
1Celecoxib (Celebrex)FDA Link
10/2018
1SteroidsIBA
01/2018
1Prednisone (Sone)FDA LinkGeneric
01/2018
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016
1Interleukin-4 (Interleukin 4)IBA
12/2016
1Oncogene Proteins (Oncogene Protein)IBA
01/2016
1Fas Ligand Protein (Fas Ligand)IBA
05/2015
1Proteasome Endopeptidase Complex (Proteasome)IBA
02/2014
1Caspase 3 (Caspase-3)IBA
02/2014
1UbiquitinIBA
02/2014
1Heme Oxygenase-1IBA
01/2014
1Granzymes (Granzyme)IBA
01/2014
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2014
1Interferon-gamma (Interferon, gamma)IBA
01/2014
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2013
1CateninsIBA
11/2013
1Interferon-alpha (Interferon Alfa)IBA
03/2013
1Ribavirin (Virazole)FDA LinkGeneric
03/2013
1Cytochromes c (Cytochrome c)IBA
02/2013
1NK Cell Lectin-Like Receptor Subfamily KIBA
02/2012
1Etoposide (VP 16)FDA LinkGeneric
12/2011
1Toxic ActionsIBA
11/2011
1methamidophosIBA
09/2011
1gamma-Aminobutyric Acid (GABA)IBA
09/2011
1MHC class I-related chain AIBA
06/2011
1GossypolIBA
06/2009
1Interleukin-1beta (Interleukin 1 beta)IBA
08/2008
1NF-KappaB Inhibitor alphaIBA
03/2006
1ParaffinIBA
05/2003
1Viral ProteinsIBA
05/2003

Therapy/Procedure

6Drug Therapy (Chemotherapy)
03/2021 - 12/2011
1Castration
03/2021
1Aftercare (After-Treatment)
10/2018
1Therapeutics
03/2012
1Surgical Amputation (Amputations)
03/2012
1Debridement
03/2012